Cell-Based Targeting of Anti-Cancer Nanotherapy to Tumors
نویسندگان
چکیده
منابع مشابه
Cell-Based Targeting of Anti-Cancer Nanotherapy to Tumors
Volume 5(4) 142-143 (2013) 142 J Cancer Sci Ther ISSN:1948-5956 JCST, an open access journal There is emerging and convincing data that certain cells, administered systemically, have a natural propensity to migrate to cancerous tissues in preclinical models. Examples of such cells include neural stem cells [1], bone marrow mesenchymal stem cells [2], umbilical cord Wharton’s jelly stem cells [3...
متن کاملNanoreporter PET predicts the efficacy of anti-cancer nanotherapy
The application of nanoparticle drug formulations, such as nanoliposomal doxorubicin (Doxil), is increasingly integrated in clinical cancer care. Despite nanomedicine's remarkable potential and growth over the last three decades, its clinical benefits for cancer patients vary. Here we report a non-invasive quantitative positron emission tomography (PET) nanoreporter technology that is predictiv...
متن کاملPrediction of Anti-cancer Nanotherapy Efficacy by Imaging
Anticancer nanotherapeutics have shown mixed results in clinical trials, raising the questions of whether imaging should be used to i) identify patients with a higher likelihood of nanoparticle accumulation, ii) assess nanotherapeutic efficacy before traditional measures show response, and iii) guide adjuvant treatments to enhance therapeutic nanoparticle (TNP) delivery. Here we review the use ...
متن کاملCell targeting in anti-cancer gene therapy.
Gene therapy is a promising approach towards cancer treatment. The main aim of the therapy is to destroy cancer cells, usually by apoptotic mechanisms, and preserving others. However, its application has been hindered by many factors including poor cellular uptake, non-specific cell targeting and undesirable interferences with other genes or gene products. A variety of strategies exist to impro...
متن کاملNanotherapy for Early Dementia: Targeting Senile Endothelium
Due to the complexity of Alzheimer's disease, multiple cellular types need to be targeted simultaneously in order for a given therapy to demonstrate any major effectiveness. Ultrasound-sensitive coated microbubbles (in a targeted lipid nanoemulsion) are available. Versatile small molecule drug(s) targeting multiple pathways of Alzheimer's disease pathogenesis are known. By incorporating such dr...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Cancer Science & Therapy
سال: 2013
ISSN: 1948-5956
DOI: 10.4172/1948-5956.1000200